CholBiome®_X3 contains OptiBiotix’s probiotic Lactobacillus plantarum LP_LDL®, monacolin K from red yeast rice and vitamin B3 as active ingredients, which provides it with a natural, powerful, multitarget and synergistic mechanism of action for cholesterol reduction. L. plantarum LP_LDL has the natural capacity to communicate and interact with our liver, one of the main organs involved in cholesterol and fats metabolism, through what scientists call the microbiome-liver axis. This way LP_LDL modulates blood cholesterol levels from the intestine. You can read a lengthier description on the About CholBiome page by clicking HERE.

Monacolin K is a compound naturally produced by the yeast Monascus purpureus when it ferments rice, which has been used for centuries in traditional Chinese medicine. It inhibits the generation of new cholesterol in the liver, preventing its buildup.

Vitamin B3 is necessary for the metabolism of fats in the cell, which promotes the reduction of blood LDL (bad) cholesterol and the increase of HDL (good) cholesterol.

CholBiome_X3 has been formulated to lower cholesterol, and contains LP_LDL, Monacolin K and Vitamin B3 comes supported with a health claim for supporting healthy cholesterol levels. CholBiome_BP has been formulated to reduce blood pressure, and contains LP_LDL, Thiamine, L-arginine and Co-EnzymeQ10, with a health claim for supporting normal heart function.

Scientific evidence with Lactobacillus plantarum LP_LDL® indicates that some effects on cholesterol levels and blood pressure may be seen after only 6 weeks. However, a full course of CholBiome® treatment is of at least 12 weeks. If a individual is taking CholBiome after CholBiome_X3 the continuation of the probiotic will simply continue its presence in the gut.

CholBiome®_X3 is a combination of three active ingredients with a multitarget and synergistic mechanism of action. Scientific evidence shows that the active ingredients within CholBiome®_X3 can cause a reduction in blood cholesterol levels of up to 36.7%. The scientific data supporting this is based on a group effect, therefore results may vary from person to person, depending on their diet, lifestyle, the time of cholesterol sampling and the testing method used.

Lactobacillus plantarum LP_LDL® was subject to an independent human study at the University of Reading, which was published in the peer-reviewed scientific journal PLoS One, in which it showed outstanding results on safety and efficacy in lowering cholesterol and blood pressure in slightly hypercholesterolaemic adults.

However the human body is extremely complex and therefore not all solutions necessarily work for everyone.

No, CholBiome®_X3 is a food supplement, hence no drugs and medical prescription is required for them.

No. If you are on any medically-prescribed regimen like statins you should not change it without consulting your doctor. Ask your doctor if CholBiome®_x3 is the right product for you.

You should always consult your doctor before taking food supplements, especially if you are pregnant, taking medication or have an existing medical condition.

The recommended daily intake of CholBiome® is one capsule/or tablet per day, and this dose should not be exceeded.
If you consume more than the daily amount by accident, you should be fine. However, if you feel any symptoms, you should seek medical advice.

CholBiome®x3 contains the patented probiotic Lactobacillus plantarum LP_LDL®, monacolin K from red yeast rice and vitamin B3 as active ingredients, which provides it with a natural, powerful, multitarget and synergistic mechanism of action for cholesterol reduction. L. plantarum LP_LDL has the natural capacity to communicate and interact with our liver, one of the main organs involved in cholesterol and fats metabolism, through what scientists call the microbiome-liver axis. This way LP_LDL modulates blood cholesterol levels from the intestine. Monacolin K is a compound naturally produced by the yeast Monascus purpureus what it ferments rice, which has been used for centuries in traditional Chinese medicine. It inhibits the generation of new cholesterol in the liver, preventing its buildup. Vitamin B3 is necessary for the metabolism of fats in the cell, which promotes the reduction of blood LDL (bad) cholesterol and the increase of HDL (good) cholesterol.

The best time to take these products is before breakfast in the morning.
The reason for this is that once we eat food, our stomach produces acids which increase its acidity, which is in turn designed by evolution to kill off harmful bacteria to prevent gut infections. Regrettably this acidity does not discriminate and equally kills bad bacteria and good bacteria like Lactobacillus plantarum LP_LDL®, which needs to be live in the intestine to elicit its natural mechanism of action. Therefore trying to avoid its exposure to stomach acidity as much as possible is highly advantageous.

No. CholBiome®_X3 is not suitable for children. Furthermore, food supplements should be stored away from the reach of children.

All the ingredients in the CholBiome® range are safe for diabetics. However, if you suffer any medical condition(s) (including diabetes) and/or are on a medically-prescribed pharmaceutical regimen, ask your doctor if CholBiome is the right product for you before taking them.

CholBiome®, CholBiome®_X3 and CholBiome_BP> are free from known allergens.

Probiotics (LP_LDL® and virtually all others) can establish in the gut only for limited periods of time. Evolution has designed the gut microbiome as a protective structure against the invasion of foreign microbes (which in nature tend to be the bad kind). As probiotics are microbes that originate from outside of the body, the native microbiome of the individual will eventually ‘flush through’ the probiotic once it has stopped being introduced after a period of time. This means continual introduction of the strain will help with a consistent presence of Lactobacillus plantarum and therefore cholesterol management effects.

Yes. Monacolin K is a natural compound generated in the fermentation of rice by the yeast Monascus purpureus, product that receives the name of red yeast rice. The use of red yeast rice in China was first documented in the Tang Dynasty in 800 AD. It has been used to make rice wine, as a food preservative for maintaining the colour and taste of fish and meat, and for its medicinal properties. A complete and detailed description of its manufacture is found in the ancient Chinese pharmacopoeia, Ben Cao Gang Mu-Dan Shi Bu Yi, published during the Ming Dynasty (1368–1644). In this text, red yeast rice is characterized as mild and useful for improving blood circulation. In China, consumption of red yeast rice has been studied in animals and humans and has been found to reduce cholesterol concentrations by 11–32% and triacylglycerol concentrations by 12–19%. Red yeast rice continues to be a dietary staple in many Asian countries, including China and Japan, with typical consumption ranging from 14 to 55 g/person/day. Red yeast rice has also been used in the Asian American community in the United States since World War II. Reducing cholesterol concentrations was shown, in several large prospective clinical trials, to be useful in the primary and secondary prevention of heart disease and the other complications of atherosclerosis. Currently monacolin K and red yeast rice are food ingredients authorised by the European Food Safety Authority (EFSA) for their use in food in the European Union. Furthermore, in 2011 EFSA acknowledged the capacity of red yeast rice of contributing to the maintenance of normal blood cholesterol levels and that this beneficial effect is obtained with a daily intake of 10 mg of monacolin K from fermented red yeast rice preparations (click here for link). This acknowledgement was granted after a thorough scientific assessment of red yeast rice’s contribution to the maintenance of normal blood cholesterol levels.

10 mg is the dose deemed as effective by the European food safety authority, EFSA (click here for info), so an effect on cholesterol is expected.

Yes, it is possible to break the tablet in half if required to make it easier, although the optimal way is to take the tablet in one. If this is still too difficult, it is possible to crush the tablet/ capsule and add to cold or room temperature food like yogurt, however, this may reduce the products effectiveness

Yes. Vitamin B3 is a natural compound that the human body cannot produce by itself and that it needs for the normal energy-yielding metabolism, amongst other functions. It therefore must be consumed in the diet in the right amounts.

Yes, completely. The recommendation is to consume CholBiome/ CholBiome_X3 for a minimum of 12 weeks to help individuals manage cholesterol levels. However, diet and lifestyle must be considered and the cholesterol level for the individual at the start of the regime.

The 12-week programme is a minimum time period based on the scientific research that was carried out with LPLDL (as found within CholBiome) and it’s effectiveness to manage cholesterol levels. In relation to whether you will need to continue taking CholBiome is not something we can simply answer. If an individual stops taking CholBiome after specific results have been achieved, there are several factors that play a role in whether it will go back up, such as lifestyle choices, diet, individual differences (genetics) and so forth. It is recommended to always ask your doctor whats best for you and to check your cholesterol levels as often as deemed appropriate by them

Unless there is specific permission given by OptiBiotix, our products are not to be resold at any point.